The boys' 100 metres competition at the 2010 Youth Olympic Games was held on 18–21 August 2010 in Bishan Stadium.

Prior to the competition, the following records were as follows.

No new records were set during the competition.

wind: –0.3 m/s wind: +0.2 m/s wind: –0.3 m/s wind: 0.0 m/s wind: +0.1 m/s