The Men's 800 metres T46 event at the 2012 Summer Paralympics took place at the London Olympic Stadium from 6 to 8 September.

[1] The T46 category is for athletes who have a single above or below elbow amputation or similar disability, with normal function in both legs.

Prior to the competition, the existing World and Paralympic records were as follows: Competed 6 September 2012 from 10:58.

rule: first 3 in each heat (Q) plus the 2 fastest other times (q) qualified.

WR = World Record.