The women's 800 metres sprint competition of the athletics events at the 2015 Pan American Games will take place between the 21 and 22 of July at the CIBC Pan Am and Parapan Am Athletics Stadium.

[1] The defending Pan American Games champion is Adriana Muñoz of Cuba.

Prior to this competition, the existing world and Pan American Games records were as follows: Each National Olympic Committee (NOC) was able to enter up to two entrants providing they had met the minimum standard (2.06.00) in the qualifying period (January 1, 2014 to June 28, 2015).

[2] All times shown are in seconds.