The women's 100 metres (T38) at the 2018 Commonwealth Games, as part of the athletics programme, took place in the Carrara Stadium on 12 April 2018.

[1] The event was open to para-sport athletes competing under the T37 / T38 classifications.

Prior to this competition, the existing world and Games records were as follows:[2] The schedule was as follows:[1] All times are Australian Eastern Standard Time (UTC+10) With six entrants, the event was held as a straight final.

[2]