Jamaica's three-Games gold medal streak in the event ended, with Usain Bolt having retired.

As the reigning World Champion, Noah Lyles came in as the favorite, but he was challenged in the US Trials by Kenny Bednarek and 17 year old Erriyon Knighton.

The second semi produced drama as Aaron Brown took an early lead with a fast start.

Lyles passed him with his typical speed coming off the turn, then eased up to save energy at the finish allowing Brown to catch him at the line.

Surprising both of them was another American high schooler, Joseph Fahnbulleh running for Liberia, coming from well off the pace to pip Lyles at the line.

In the final, De Grasse reacted fastest and his Canadian teammate Brown got a good start, both of them making up ground on the stagger of the Americans to their outside, Bednarek and 17 year old Erriyon Knighton, respectively.

[3] With his score, De Grasse finally moved into the top 10 of all-time in the 200m, a status foretold six years earlier with a wind-aided 19.58 while competing for the University of Southern California.

Due to the COVID-19 pandemic, the period was suspended from 6 April 2020 to 30 November 2020, with the end date extended to 29 June 2021.

Withdrawn after qualification by standard or ranking: Miguel Francis, Benjamin Azamati-Kwaku, Zharnel Hughes, Christophe Lemaitre, Mouhamadou Fall, Méba-Mickaël Zeze, Jeffrey John, Paulo André de Oliveira.