The women's marathon T54 event at the 2020 Summer Paralympics in Tokyo, took place on 5 September 2021.

The T54 category is for wheelchair athletes with no leg function, but near full arm function and reasonable to normal trunk function.

Typically this may be caused by a lower spinal cord injury or spinal cord birth defect.

Prior to the competition, the existing records were as follows:[1] The race took place on 5 September 2021, at 6:40:[2]