The men's 110 metres hurdles at the 2022 Commonwealth Games, as part of the athletics programme, took place in the Alexander Stadium on 2 and 4 August 2022.

Prior to this competition, the existing world and Games records were as follows: The schedule was as follows:[1] All times are British Summer Time (UTC+1) The first round consisted of two heats.

The three fastest competitors per heat (plus two fastest non-automatic qualifiers) advanced to the final.

[2] The medals were determined in the final.

[3]