The entire 2000s were spent in the third level, but several players continued to make the transition to the first team, including the likes of David de Gea, Álvaro Domínguez, Antonio López, Gabi, Mario Suárez, Koke, Ignacio Camacho, Saúl Ñíguez, Thomas Partey and Lucas Hernandez.

Note: Flags indicate national team as defined under FIFA eligibility rules; some limited exceptions apply.

Note: Flags indicate national team as defined under FIFA eligibility rules; some limited exceptions apply.

Note: Flags indicate national team as defined under FIFA eligibility rules; some limited exceptions apply.

Note: This list includes players that have appeared in at least 100 top league games and/or have reached international status.