Shot in black-and-white, the film was produced by Elio Ippolito Mellino and stars Alberto Lupo, Susanne Loret, and Sergio Fantoni set in France.

When a stripper (Susanne Loret) becomes disfigured in a car accident, a scientist (Dr. Levin, played by Alberto Lupo) develops a treatment to restore her beauty by injecting her with a special serum.

During a meeting with police, a restored-to-humanity Dr. Levin speculates that the Hiroshima survivors' tales of a mutated killer are due to psychological strain from the radiation damage to their bodies.

[3] The script for the film recalls Georges Franju's Eyes Without a Face, which had been released in Italy several months before Atom Age Vampire.

[1] In Italy, a contemporary review in La Stampa gave a brief plot and stated neither the directing nor the actors (specifying Alberto Lupo, Susanne Loret, Sergio Fantoni and Ivo Garrani) make it any less absurd or clumsy.

[3] In 2011, British artist Adam Roberts made Remake, a scene-for-scene reshoot of the original film using the dubbed English soundtrack, but minus the presence of any of the characters.