Son of Giovambattista Murri, a magistrate, deputy of the Repubblica Romana, and Teodolinda Polimanti, the mother.

Guido Baccelli remained impressed with Murri’s studies on "The nature of the morbose process of the severe jaundice" published in 1868 on the Florentine magazine Lo sperimentale.

Here, Murri confuted Friedrich Theodor von Frerichs' theories relating the disease to a deep change in the properties of the blood fluid, whereas the prevalent opinion was that the illness was originated by a mechanic cause.

Two years later, in 1876, Ruggero Bonghi, Minister of the public education, made Murri the director of the medical clinic of the University of Bologna.

After getting his degree, he moved to Paris, where he followed the lectures of Ernest Bazin, Louis Fournier and Armand Trousseau.

[citation needed] In 1905, he went back, at the continuous request of the students, to teaching after having removed himself because of the events regarding the death of his son-in-law (the Murri case, see below).

[citation needed] In his work "Sulla natura del processo morboso dell’itterizia grave", he linked jaundice to some changes in the properties of blood.

In his other work, "Lezioni di clinica medica", he highlighted that a meticulous observation and analysis of phenomena was necessary in order to have a correct diagnosis and adequate therapy.

Murri’s method, indeed, was made up by the listening, the physical exam, the vision of the assessments, the experimental verification and the attention to facts.

[citation needed] Murri is particularly concentrated on the observation and analysis of the events in order to reach the right diagnosis and also an appropriate therapy.

[6] Bologna in the beginning of the 20th century was the scene of a crime considered as the first big "show trial".

The murderer was presumed to be Tullio, instigated by the sister Linda who suffered greatly by her husband mistreatments; it was exactly Augusto Murri that reported his son.

The case was also taken as a pretext by the Catholic daily newspaper "L' Avvenire" for a campaign against the laical rationalism, the socialism and the Masonry.

Gianna Murri said that her father, after going out of prison, wrote a memoir where he told the truth about the murder and the "Biondino", and the latter confessed all to a priest before dying.

The reason why Tullio was blamed for the murder was for his father, in order not to make him suffer about the adultery of the sister Linda.