[6] Stylistically, it steps up the pace from other recent Meat Beat Manifesto albums, using elements of dub, hip-hop, industrial, breakbeat and more, and it is regarded as a partial return to the early industrial sound of the band in the late 1980s.

[7] The album has also been described as Dangers' take on dubstep, though he has stated that Meat Beat Manifesto has always utilized the underlying concepts of that particular genre.

[5] Autoimmune is the first Meat Beat Manifesto album with Danger's vocals since Actual Sounds + Voices in 1998; he appears on the track "Solid Waste".

Most of the remaining songs that were excised from the original double-disc concept were later released on an EP available only on the Autoimmune tour.

"Bush of Lies" was first released as a free download on the band's official website.