Autopista San Antonio-Santiago (formerly known as Autopista del Sol) is a toll highway that runs from Santiago, Santiago Metropolitan Region to San Antonio, Valparaíso Region, in central Chile.
Its total length in Santiago Metropolitan Region is 85 km (53 mi).
It meets Vespucio Norte Express close to the metro station that bears its name.
Once out of Santiago city limits, the highway continues southwesterly through Peñaflor, Talagante, and El Monte.
After running for 104.6 km (65.0 mi), the main section of the highway terminates at an interchange with Route G-94-F.