Butantã (Portuguese pronunciation: [butɐ̃ˈtɐ̃], from the tupi for "crushed soil") is a district of the city of São Paulo, Brazil.

It is part of the homonymous subprefecture, located on the west bank of the Pinheiros River.

The district hosts the main campus of the University of São Paulo.

All of them have a predominantly residential profile, with some commercial corridors: the avenues Vital Brasil, Corifeu de Azevedo Marques, Engenheiro Heitor Antônio Eiras Garcia, Eliseu de Almeida, Comendador Alberto Bonfiglioli and Professor Francisco Morato, as well as streets such as Alvarenga, Camargo and MMDC.

[1] Butantã is also crossed by the initial kilometers of the Raposo Tavares highway.