Avesnes-sur-Helpe (French pronunciation: [avɛn syʁ ɛlp] ⓘ; West Flemish: Avenne aan de Helpe), Picard: Avinne-su-Helpe) is a commune in the Nord department in northern France.

The house of Avesnes played an important role in the low countries, including several Counts of Holland.

Historically a part of the County of Hainaut, it became French in 1659 as a result of the Treaty of the Pyrenees, and was fortified by Vauban, although it was captured by Prussia in 1815.

The high school in the region is the Lycée Jesse de Forest, named for an Avesnes native son who was responsible for the earliest settlement of the Dutch and Huguenots in what is now New York.

(Avesnes-sur-Helpe, Cartignies, Damousies, Dimechaux, Dimont, Felleries, Larouillies, Lomme, and Ramousies use the same arms.)