Their stronghold in the riding is in and around Mont-Joli, and for the most part, they carried the rural areas, particularly in the northern portion of the district.

The area around Amqui offered the most diverse range of support, with all parties doing fairly well, but with the Bloc coming out on top.

Matane, and the rural regions surrounding it, were the best portions of the seat for the Liberals, although they had to contend with strong support for the Bloc as well.

Avignon—La Mitis—Matane—Matapédia was created by the 2012 federal electoral boundaries redistribution and was legally defined in the 2013 representation order.

Consequently, the 2023 representation order for Quebec abolished Avignon—La Mitis—Matane—Matapédia and divided its territory between the neighbouring ridings of Gaspésie—Les Îles-de-la-Madeleine and Rimouski-Neigette—Témiscouata—Les Basques.