[1] It is contained between Eastern Avenue NE to the south, Queens Chapel Road (MD-500) to the east, and the Northwest Branch Anacostia River to the north and west.

Avondale borders the neighborhoods of Hyattsville, Chillum, Green Meadows, and Mount Rainier in Prince George's County, Maryland.

[2] The settlement of Avondale began in the late 1930s as a small residential subdivision at the intersection of Eastern Avenue and Queens Chapel Road.

Developers of the Avondale neighborhood promoted the area's very close proximity to Washington D.C. as well as its already established utility supplies.

[6] WMATA scrapped that plan in 1978 due to strong opposition from many residents living in the Avondale Chillum neighborhoods and in the Kirkwood Apartments in Hyattsville.

[6] Even though construction of the Green Line train tracks between the Fort Totten and West Hyattsville Metro Stations was supposed to begin in 1986 and have been completed by the end of 1990, construction of the Green Line train tracks between the two stations was delayed until 1990 and was only completed on December 11, 1993, due to the lack of funding available during the time.

[7] In 1931, De La Salle College–a religious study house for the Roman Catholic teaching order Christian Brothers–was opened.

For many years, it had been the only convenient location for many senior citizens and longtime residents of Avondale and Mount Rainier to buy groceries.

Avondale Neighborhood Park is located at the intersection of La Salle Road and Ingraham Street, just north of the Maryland-Washington D.C. line (Eastern Avenue NE).