Avram Hershko (Hebrew: אברהם הרשקו, romanized: Avraham Hershko, Hungarian: Herskó Ferenc Ábrahám;[1] born December 31, 1937) is a Hungarian-Israeli biochemist who received the Nobel Prize in Chemistry in 2004.

He was born Herskó Ferenc in Karcag, Hungary, into a Jewish family,[2] the son of Shoshana/Margit 'Manci' (née Wulc) and Moshe Hershko, both teachers.

During the final days of the ghetto, most Jews were sent to be murdered in Auschwitz, but Avram and his family managed to board trains that took them to a concentration camp in Austria, where they were forced into labor until the end of the war.

He received his MD in 1965 and his PhD in 1969 from the Hebrew University of Jerusalem-Hadassah Medical Center.

Along with Aaron Ciechanover and Irwin Rose, he was awarded the 2004 Nobel Prize in Chemistry for the discovery of ubiquitin-mediated protein degradation.