Ayşe Hümaşah Sultan[2] (Ottoman Turkish: عایشه سلطان, lit.
'life' and 'Şah's phoenix'; 1541 – 1598) was an Ottoman princess, the only daughter of Mihrimah Sultan and Rüstem Pasha (Grand Vizier 1544–53, 1555–61).
Consequently, her sons and daughters, who as great-grandchildren in the female line of a Sultan should have neither titles nor be considered members of the imperial family, were instead entitled to the titles of Sultanzade for males and Hanımsultan for females, as was rule for the children of a Sultana.
[6] Ayşe Hümaşah, her mother, and her cousin would all imitate the communication style ushered in by her grandmother Hürrem, whose letters to the Sultan are known for their colourfulness, charm, and smoothness.
[15] According to rumors, Ayşe Hümaşah Sultan would also have married Mahmud Hudayi Pasha.
In fact, all of this they reported to Behram Kethüda, who by sultan's order was to attend to Ayşe Hümaşah after Mihrimah's death.
When her son Mehmed Bey was installed as sancakbey of Herzegovina in 1592, she soon wrote him a letter of recommendation for the Ragusans.