In addition, she also provided the voice of Misa Amane in Death Note, Konata Izumi in Lucky Star, and Lucy Heartfilia in Fairy Tail.

[6][7] After starting her acting career, Hirano began to appear in commercials and received her first role as a voice actress at 14 years old in the 2001 anime series Angel Tales.

[11][14] She also won in the Voice Acting category at the 2007 Tokyo Anime Awards for her role as the lead character in The Melancholy of Haruhi Suzumiya.

[19] In 2007, she continued to enjoy great success in her career, landing the role of Konata Izumi in the anime version of Lucky Star.

[13] In 2008, at the second Seiyu Awards, she won for Best Lead Actress, and also for Best Singing along with cast members of Lucky Star for the series' opening theme "Motteke!

[21] Citing a need for a new agency that was more ideal for her career wishes, she announced on August 12, 2011, that she had left Space Craft Entertainment.

[23] Days later, on August 27, she posted a message on her Twitter account, confirming that she had resumed new voice acting roles in anime.

[24] In 2016, after a stint in the musical The Mystery of Edwin Drood in Tokyo, Hirano spent four months studying English and voice in New York.

[30] Hirano's first solo single under the record label Lantis was "Breakthrough", which was released on March 8, 2006; the title track was used as the opening theme of the visual novel Finalist.

[39] Hirano released her seventh single "Unnamed World" on April 23, 2008; the title track was used as the ending theme to the anime series Nijū Mensō no Musume.

[43] She then released her ninth single "Super Driver" on July 22, 2009; the title track is used as the opening theme of the second season of The Melancholy of Haruhi Suzumiya.

[53] This was followed by the song "Zutto Kitto" (ずっと きっと) which was released on August 15, 2012;[54] the title track is used as the ending theme to the anime film Fairy Tail the Movie: Phoenix Priestess.

[66] Once The Melancholy of Haruhi Suzumiya broadcast in 2006, Hirano received widespread media attention and popularity, which led her to be known as a "super idol" in the voice acting industry.

[70] Beginning in 2010, Hirano drew criticism from her anime otaku fanbase when she openly discussed her dating and sex life on the variety show Goût Temps Nouveau,[71][72] as well as the implication that she was abandoning voice acting in favor of a career in mainstream entertainment.

[73][74][75] In early 2011, an acquaintance of a Lantis employee leaked that Hirano had sexual relations with three of her band members, leading to the dismissal of all four of them; in August 2011, Japanese magazine Bubka published photos of their affair.

[76] The incidents caused several fans to destroy her merchandise, create petitions to remove her from her role in Kizumonogatari,[76] and send death threats.