Ayrshire (/ˈɛərʃər/)[2] is a city in Palo Alto County, Iowa, United States.

In October 1882 the rails reached the location of Ayrshire, and a depot was built the following month.

At one time it had two banks, two grocery stores, blacksmith shop, livery stable, creamery, hotel, at least two barber shops; Lutheran, Catholic, Methodist and Baptist churches; five gas stations, grain elevator, two cafes, a locker plant, a pharmacy, a lumber yard, two beer halls and several other businesses.

In 1972, the town drew national attention for having the youngest mayor in America.

[5] The rail line, by then part of the Chicago and North Western Railway, was abandoned in the 1980s, and torn up.

[8] According to the United States Census Bureau, the city has a total area of 0.21 square miles (0.54 km2), all land.

52.0% of all households were made up of individuals, and 24% had someone living alone who was 65 years of age or older.

34.8% of all households were made up of individuals, and 18.0% had someone living alone who was 65 years of age or older.

None of the families and 4.8% of the population were living below the poverty line, including no under eighteens and 7.1% of those over 64.

The number of residents decreased from 202 in 2000 to 143 in the 2010 census, less than half the population a century earlier, 329 in 1900 and 337 in 1910.

It was a part of the Ayrshire Community School District until July 1, 1983, when it merged into Ruthven-Ayrshire.