He made his directional debut with the 1989 television serial Circus starring Ashutosh Gowariker and Shah Rukh Khan.
He made his film debut with Raju Ban Gaya Gentleman (1992) starring Khan and Chawla.
His next project, Yes Boss (1997) starring Aditya Pancholi, Shah Rukh Khan and Juhi Chawla.
In 1999, Mirza set up a production company called Dreamz Unlimited with Juhi Chawla and Shah Rukh Khan.
In 2007, Mirza returned to directing and released his next film titled Kismat Konnection in 2008, starring Shahid Kapoor and Vidya Balan.