BR-459 is a federal highway that connects Poços de Caldas, in Minas Gerais, to Lorena, in the state of São Paulo.

[1] Its extension is planned to the municipality of Angra dos Reis, in the state of Rio de Janeiro.

[2] In the state of Minas Gerais, the BR-459 is 215.4 km (133.8 mi) long[2] and passes through the municipalities of Poços de Caldas, Caldas, Santa Rita de Caldas, Ipuiúna, Senador José Bento, Congonhal, Pouso Alegre, Santa Rita do Sapucaí, Cachoeira de Minas, Piranguinho, Itajubá, Wenceslau Braz e Delfim Moreira,[3] located in the Mesoregion of the South and Southwest of Minas.

[6] In the state of São Paulo, BR-459 is 32.2 km (20.0 mi) long and crosses the municipalities of Piquete and Lorena, located in the Mesoregion of Vale do Paraíba Paulista.

In São Paulo, the layout of this extension includes a stretch that coincides with the BR-116 in the municipalities of Lorena and Guaratinguetá and the entire SP-171 highway, passing through Cunha.