[3] Zareen started her singing career in 1948 with a Radio station at the age of seven where she used to sang songs in regional languages such as Pashto, Punjabi, Hindko, Urdu, Seraiki, and Persian.
[3] During her lifetime career, she later participated in a mehfil called Mehfil-e-Samaa and used to sung Sufi devotional songs where she was recognized as a "spiritual daughter" of a Pashto composer Rafiq Shinwari.
Before her musical journey was started, her father Ustad Abdur Rahim Khan, a tabla player introduced her to the Pakistan Broadcasting Corporation (PBC) for an audition.
[4] Zareen's prominent songs include "Alaka Bali Ma Narawa", "Ma Pre Sezi Ze", "Da Bama Olwegy Che Za", "Jenaki Daly Daly", "Tambal Wahi", and numerous other songs, leading her to earn national recognition.
It is believed Zareen and her nephew lived in a rented house in Peshawar, and later requested the provincial government-led cultural department of the Government of Khyber Pakhtunkhwa for financial assistance.
After the minister's visit was published by the news media, it is believed her home appeared crowded by the mortgage lenders demanded a recovery of their loans borrowed by Zareen.