The Baldwin DS-4-4-750 was a four-axle 750 horsepower (560 kW) diesel-electric switcher locomotive built by the Baldwin Locomotive Works at it Eddystone, Pennsylvania factory between 1949 and 1951.

It was the low power companion in Baldwin's catalog to their DS-4-4-1000 and the S-12.

Page 40 of the Dolzall brothers book "Diesels from Eddystone" describes the DR-4-4-750 as a "Horsepower boost for a lagging seller."

Baldwin dropped the DR-4-4-660 model and introduced the new 750 HP DR-4-4-750.

The Atchison, Topeka & Santa Fe (AT&SF) purchased nine in August 1948 and 21 units were sold in 1949 to six different customers.