Cooperation among Ghana Airways, Gambia International Airlines, and the Ghanaian and Gambian governments had given rise to the service.

[7] In June 2006, North American Airlines inaugurated a link to Baltimore using Boeing 767s; the route lasted seven months.

[8][9][10] The head office of the Gambia Civil Aviation Authority is located on the airport property.

[11] In the event of an emergency on any of the NASA Space Shuttles, Banjul International Airport had been selected as an augmented landing site.

[12][13] In 2001 NASA announced that Banjul airport would no longer be used as an augmented landing site because future shuttle launches would take place at inclinations of up at 51.6 degrees to reach the International Space Station, making air bases in Spain and France more suitable for an emergency landing.