[2] According to the Arab historian al-Sam'ani, the members of the Banu Nadir tribe are the descendants of al-Nadir, a Jewish man who migrated from Judea to Arabia.
They earned their living through agriculture, usury, and trade in weapons and jewels, maintaining commercial relations with Arab merchants of Mecca.
[7] Muhammad emigrated to Yathrib in September 622, he arrived with a group of his followers, who were given shelter by the members of the indigenous community who were known as the Ansar.
[15] After the Battle of Badr, one of the Banu Nadir's chiefs Ka'b ibn al-Ashraf, went to the Quraish in order to lament the loss at Badr and to incite them to take up arms to regain lost honor, noting the statement of Muhammad: "He (Ka'b) has openly assumed enmity to us and speaks evil of us and he has gone over to the polytheists (who were at war with Muslims) and has made them gather against us for fighting".
Some sources suggest that during his visit to Mecca, Ka'b concluded a treaty with Abu Sufyan, stipulating cooperation between the Quraysh and Jews against Muhammad.
[22] After defeat by the Quraish at the Mount Uhud in March, 625, the Banu Nadir challenged Muhammad as the leader of Medina.
[26] Huyayy ibn Akhtab decided to put up resistance, hoping also for help from the Banu Qurayza, despite opposition within the tribe.
[5] The Nadir were forced to surrender after the siege had lasted for 14 days, when the promised help failed to materialize and when Muhammad ordered the burning and felling of their palm-trees.
[5] A number of Jews who had formed a party against Muhammad, including Sallam b. Abu'l-Huqayq, Kenana ibn al-Rabi and Huyayy b. Akhtab, the chiefs of Nadir who had gone to Khaybar, together with two chiefs from the tribe of B. Wa'ili went to Quraysh and invited them to form a coalition against Muhammad so that they might get rid of him altogether.
[29] Banu Nadir promised half the date harvest of Khaybar to nomadic tribes if they would join the battle against Muslims.
[30][31] Abu Sufyan, the military leader of Quraysh, with the financial help of Banu Nadir had mustered a force of size 10,000 men.
He had however adopted a new form of defense, unknown in Arabia at that time: Muslims had dug a trench wherever Medina lay open to cavalry attack.
[32] Abu Sufyan's troops were unprepared for the fortifications they were confronted with, and after an ineffectual siege lasting several weeks, the coalition decided to go home.
All Muhammad's emissaries fell upon the thirty Jewish companions and killed them except one man who escaped on his feet.
[35] Abdullah bin Unays is the assassin who volunteered and got permission to kill Banu Nadir's Sallam ibn Abu al-Huqayq at a previous night mission in Khaybar.
Although the Jews put up fierce resistance, the lack of central command and preparation for an extended siege sealed the outcome of the battle in favor of the Muslims.