He served as a division commander in the Grande Armée of Emperor Napoleon in 1805 and 1807, playing a leading role at the Battle of Friedland.

Command of the division passed to Marie-François Auguste de Caffarelli du Falga, who led it at the Battle of Austerlitz[4] after Bisson was badly wounded during the pursuit at the passage of the Traun River.

[2] At the end of the War of the Fourth Coalition, Napoleon recalled Bisson to command one of Marshal Michel Ney's VI Corps infantry divisions.

[6] However, as Ney's corps advanced deep into the enemy positions, it ran into intense artillery fire which caused heavy losses.

[7] As their enemies recoiled, Ney's men rallied and returned to the assault, helping to drive the Russians from Pravdinsk (Friedland) around 8:00 PM.

The rebels soon forced Bisson to surrender with his trapped soldiers and the eagle of the 3rd Line Infantry Regiment[10] near Innsbruck between 11 and 13 April 1809.

One observer claimed he could finish off eight bottles of wine for lunch while conversing pleasantly and issuing orders to his troops.