[citation needed] After earning her M.D., Bollier joined her father's practice at Surgicenter of Kansas City.

[3] She then began to volunteer with the Center for Practical Bioethics and became active with the Shawnee Mission Education Foundation Board.

I'm looking forward to being in a party that represents the ideals that I do, including Medicaid expansion and funding our K–12 schools.

"[12] Bollier said that the "breaking point" had been the Kansas Republican Party's inclusion of anti-transgender language in its platform.

[13] On October 16, 2019, Bollier announced that she would run in the 2020 election for the United States Senate seat being vacated by the retiring Pat Roberts.

[14] The next day, former United States Attorney for Kansas Barry Grissom dropped out of the race and endorsed Bollier.

[15] Grissom's withdrawal from the race came despite his having raised almost half a million dollars in contributions during the previous quarter.

[20] On September 1, 2020, she published a list of 75 Republican current and former Kansas officeholders who supported her campaign.