Barbara Lee Keyfitz is a Canadian-American mathematician, the Dr. Charles Saltzer Professor of Mathematics at Ohio State University.

In her research, she studies nonlinear partial differential equations and associated conservation laws.

[5] Keyfitz is the 2005 winner[6] of the Krieger–Nelson Prize of the Canadian Mathematical Society, the 2011 Noether Lecturer of the Association for Women in Mathematics,[1] the 2012 winner of the SIAM Prize for Distinguished Service to the Profession, and the 2012 AWM-SIAM Sonia Kovalevsky Lecturer.

[3] She was interviewed by Patricia Clark Kenschaft in her book Change is Possible:Stories of Women and Minorities in Mathematics.

[8] She is also a fellow of the American Association for the Advancement of Science, the Society for Industrial and Applied Mathematics[1] and the Fields Institute.