[1] Riegel has published over 600 papers on various topics regarding self-care, such as treatment adherence, sleep, condition monitoring, and self-management of symptoms associated with chronic illness.

She has been a Senior Fellow, Leonard Davis Institute University of Pennsylvania since 2003, and as Co-Director for the International Center for Self-Care Research since 2018.

[7] Riegel has focused her research on self-care with particular attention on treatment adherence, sleep, condition monitoring, and self-management of symptoms.

While keeping in view that heart failure was a primary reason for hospital readmissions, she began studying these issues early in her career while a Clinical Researcher in an acute care setting.

[9] Furthermore, she highlighted the role of family in terms of facilitating a rapid improvement in self-care self-efficacy and a decrease in depressive symptoms, particularly among women.

[10] Riegel conducts many research projects through her international collaborations with colleagues in Italy, Sweden, Australia, Hong Kong, Brazil, and beyond.

She also states that “the notable feature of this work is the presentation of practical examples of programs that have been developed to manage heart failure in the outpatient setting.