[16] On June 24, 2004, one week after appointing its new president, Gloria Bromell Tinubu, the college learned that it had lost its accreditation due to what the Southern Association of Colleges and Schools said was a failure to comply with SACS Principles and Philosophy of Accreditation (Integrity), as the school "awarded degrees to nearly 30 students in the adult program who SACS determined hadn't fulfilled the proper requirements".

[19][20] In February 2006 a committee of the General Assembly Council of the Presbyterian Church (USA) voted to continue the denomination's financial support for Barber–Scotia, noting that its physical facilities were "substantial and well-secured" and that the school was undertaking serious planning for the future.

"[22] McLean was replaced by President David Olah who accepted the position without payment and the college re-opened in 2006 with a limited number of students.

[23] During this time, the "previous attempts to revive the college [which] have centered on an entrepreneurial or business curriculum" were formally abandoned "in favor of focusing more on religious studies".

In September 2016, the newly elected Board of Trustees hired David Olah as president to once again lead the college, at which twelve students were enrolled.

After meetings with community leaders, it was determined possible uses for campus buildings as of September 2020 included a school, a museum, and a business center.

[33] Douglass and Chairwoman Karen M. Soares, with the aid of Congresswoman Alma Adams, were able to get a 21-year, estimated, $12 million loan forgiven.

The program provided low-cost capital to finance improvements to the infrastructure of the nation's Historically Black Colleges and Universities.

[34] The Association for Biblical Higher Education said the college had inquired about accreditation but as of July 2021 had not started the process, which would take eight to ten years.

[37] An August 2022 article in the Independent Tribune said, "seven of the 15 buildings are deemed unoccupiable", that six others needed violations to be corrected, and that the college had awarded no degrees in 18 years.

College leaders announced a partnership with the unaccredited, for-profit Medcerts for health services training online.

The Cabarrus County tax assessor was determining whether the college still qualified as a nonprofit; if not, land and buildings worth almost $12 million could be sold.

[40] A July 6, 2023 news release stated that trustees appointed Chris V. Rey, former mayor of Spring Lake, North Carolina, to succeed Flemmings as president.

[citation needed] Barber-Scotia were members of the United States Collegiate Athletic Association (USCAA) until 2015.