[1][3] He has had film roles in Strictly Ballroom, Cosi, The Dressmaker, Kiss or Kill, Dead Letter Office, The Visitor, The Great Gatsby, Legend of the Guardians: The Owls of Ga'Hoole, Love's Brother (see Filmography).

In 2015 Otto voiced the role of Mayor Wilberforce Cranklepot, a goanna, in Blinky Bill the Movie.

Otto married Lindsay, with whom he has a daughter Miranda (an actress), born in 1967 in Brisbane.

[citation needed] With his second wife Susan "Sue" Hill,[7] Otto has a son, Eddie (a teacher and professional cricket coach), and daughter, Gracie (a filmmaker and actress), born in 1987 in Sydney.

[10] [11] Otto received an AACTA Award for Best Supporting Actor in Strictly Ballroom and was nominated for Bliss, Cosi and The More Things Change.... Barry Otto at Randwick in Sydney on the Australian Film Walk of Fame.