Bartolomeo Spina (born at Pisa about 1475; died at Rome, 1546) was an Italian Dominican theologian and scholastic philosopher.
He was involved in the attempted take-over of the Milanese convent of Sant'Eustorgio by the Observant friars of the Congregation of Lombardy before becoming master of studies at the Dominican studio in Bologna in 1513–4.
In July, 1542, he was made Master of the Sacred Palace by Pope Paul III, and during the four years that he discharged the duties of that office he rendered services to the Holy See and to the Fathers of the Council of Trent, regarding many difficult and mooted questions.
As Master of the Sacred Palace, he was said to have wanted to move against Copernicus' De revolutionibus, only stopped by his death.
These included Thomas Cajetan, whom he clashed with starting in 1518; Ambrose Catharinus, whom he accused to Paul III in 1546; and Pietro Pomponazzi.