The original intent of this book was to feature the exploits of Batman and his extended family, such as Alfred Pennyworth, Batgirl, Nightwing, Robin, Oracle, and Catwoman, among others.

Contributors to this section include Jim Lee, John Byrne, John Buscema, Eduardo Risso, Jordi Bernet, José Luis García-López, Kyle Baker, Harlan Ellison, Dave Gibbons, Gene Ha, Gene Colan, Enrique Breccia, Claudio Castellini, Dick Giordano, Christian Alamy, Jason Pearson, Mike Wieringo, Alan Davis, Chris Bachalo, Denys Cowan, John Watkiss, Mike Kaluta, and Whilce Portacio.

Grayson's run as writer ended at issue #32 with the critically-acclaimed one-issue story "24/7" showing a full day in the life of Batman.

Although Batman: Gotham Knights was originally uncollected at the time of publication, the majority of Devin Grayson's run as writer of the series has since been collected into two trade paperback volumes.

Issue #10, "Guardian", was included in Legends of the Dark Knight: José Luis García-López, published in November 2021.

[5] The backup stories from issues #17-49 Batman: Black and White Volume 3 were published as a comics-sized hardcover in May 2007,[6] while a softcover edition was released in 2008.