[1]: 95–99 Marshal Caxias had left Villeta at 02:00 on the 21st, and was ready to storm the Lomas Valentinas range by noon.

Two columns of infantry, one under general José Luís Mena Barreto attacking the western defenses at Itá Ybaté, and another under general Jacinto Machado de Bittencourt [pt] aided by cavalry under general Andrade Neves attacking the northern defenses at Loma Acosta, where the hill of Cumbarity was located.

[1]: 95–96 On December 22, Argentine and Uruguayan troops advanced towards Lomas Auxilio.

[1]: 97–98 Nurse Ramona Martínez was enslaved by López, but due to her work fighting and encouraging troops at the battle, became known as "the American Joan of Arc".

[2] López made his escape with the Aca Vera cavalry acting as his escort.