Battling with Buffalo Bill is a 1931 American pre-Code Western serial film directed by Ray Taylor and starring Tom Tyler, Lucile Browne, William Desmond, Rex Bell, and Francis Ford.

Based on the book The Great West That Was by William F. "Buffalo Bill" Cody, the film is about a cowboy named Buffalo Bill who goes up against a shady gambler who is attempting to scare off the townspeople so he can gain possession of a gold strike.

Cody's book was also used as the inspiration for the studio's highly successful 1930 serial The Indians Are Coming.

The plot is a variation on the standard B-Western "Land Grab" plot: Gold has been discovered in the area and gambler Jim Rodney intends to make sole claim to it by pushing the rightful owners off the land and taking it for himself.

Along with the more successful The Indians Are Coming (1930) this serial was based on the book "The Great West That Was" by Buffalo Bill Cody.