It organizes campus events, promotes Baylor's intercollegiate athletic teams and cares for the university's live bear mascots.

"[5] The Chamber also provided new band uniforms, using monetary pledges solicited from the Baylor and Waco communities.

Saturday's events begin with the nation's oldest and largest collegiate Homecoming Parade.

[10] Diadeloso is a campus-wide holiday each spring that the Chamber also organizes to give students time to relax.

Events include student organization booths, intramural tournaments, a dog show, food, and a music festival.

[10] In 2022 the Chamber of Commerce was not allowed to host Diadeloso due to a hazing incident.

Other activities that the Chamber has put on include the sale of Slime Caps (1920), the Card Section (1952–1989), Football Program Sales (1960), Baylor University Athletic Hall of Fame (1960), Bear Bash (1968), the Baylor Faculty Jamboree (1990), the Robert L. Reid Distinguished Lecture Series (1992), and Banners.

[10] John Clifton, a pledge of the Baylor Chamber of Commerce, died on October 10, 1967.

[13] On October 10, 1967, John Clifton, a pledge from Crosby, Texas, died of asphyxiation during hazing.