Some of the clans that lived in Bayt Nabala include the AlHeet, Nakhleh, Safi, AL-Sharaqa, al-Khateeb, Saleh and Zaid families.

[11] In the 1596 tax record, Bayt Nabala was categorized under the Liwa of Gaza, with a population of 54 Muslim households, an estimated 297 people.

[12] In the 17th century, the village received an influx of refugees from neighboring Beit Qufa, who had to abandon their home due to unsettled conditions.

During the 18th and 19th centuries, Beit Nabala belonged to the Nahiyeh (sub-district) of Lod that encompassed the area of the present-day city of Modi'in-Maccabim-Re'ut in the south to the present-day city of El'ad in the north, and from the foothills in the east, through the Lod Valley to the outskirts of Jaffa in the west.

[14] According to historian Roy Marom "Bayt Nabālā was a major hub for the Qays and Yaman conflicts in the area."

[19] In 1882, the PEF's Survey of Western Palestine described Bayt Nabala as being of moderate size, situated at the edge of a plain.

[20] Since the end of the 19th century, the inhabitants of Beit Nabala cultivated the lands of the deserted village of Jindas.

"[5] According to the Palestinian Heritage Foundation, Beit Nabala dresses (together with those of the village of Dayr Tarif), "were usually done on cotton, velvet or kermezot silk fabric.

Taffeta inserts embroidered in Bethlehem style couching-stitch in gold and silk cord were attached to the yoke, chest panel, sleeves and skirt.