Bayuvi Dupki–Dzhindzhiritsa (Bulgarian: Баюви дупки–Джинджирица), also spelled Doupki–Djindjiritza, is a nature reserve in Pirin National Park, located in the homonymous mountain range in south-western Bulgaria.

[5] Among the rare and endemic vascular plants are European blueberry (Vaccinium myrtillus), Aquilegia aurea, Oxytropis urumovii, great yellow gentian (Gentiana lutea), golden root (Rhodiola rosea), edelweiss (Leontopodium alpinum) and Pirin poppy (Papaver degenii).

Some Macedonian pines reach heights of over 45 m and diameter of more than 2 m; some individual trees have an age of over 1000 years.

[2] The higher sections of the reserve are covered by dwarf mountain pine (Pinus mugo) formation reaching age of 100 years.

Other important conservation species include brown bear, gray wolf, European pine marten, beech marten, red fox, roe deer, wild boar, red squirrel, western capercaillie, golden eagle, hazel grouse, Eurasian three-toed woodpecker, spotted nutcracker, etc.