The base was probably named for James Beane, a US Army Air Force World War I flying ace.
With the end of World War II, Beane Field was reduced to a skeleton staff.
The airfield's primarily unit was the MATS 6th Weather Squadron (Regional), with overall command of the base being that of the 24th Composite Wing, headquartered at Ramey AFB (now Coast Guard Air Station Borinquen), Puerto Rico.
Agreements for the base's disposition were subsequently reached with the United Kingdom and, later, the Saint Lucia government upon that state's independence.
In 1966, St. Jude's Hospital was founded in the abandoned medical facility of the base by a nun from Kansas, Mary Irma Hilger of the Sisters of the Sorrowful Mother.