Beastro & Barley is a restaurant and bar in a historic hotel building in the Second Empire style at 125 East Main Street in Reedsburg, Wisconsin, United States.

The two-storey red brick structure with stone trim and a mansard roof was designed by Edward M. Hackett and constructed in 1886 for $10,000.

It includes arched window frames, brick detailing on the facade and a small porch with ornamental metal balustrade on the second floor.

The building now houses the Beastro & Barley restaurant and bar downstairs and a single large apartment upstairs.

Beastro & Barley is known for its trademarked "Reedsburger", a hamburger prepared with locally sourced Bison.