Born in Rome in 1993, Grannò attended a musical academy in Prato and graduated from East 15 Acting School in London in 2016.

[1][2] She began her stage career and made her television debut with a small role in Don Matteo in 2014.

[4] In 2019, Grannò played her first leading role in the feature film Wonder When You'll Miss Me, directed by Francesco Fei.

[7] Since 2020, Grannò has starred in the Italian medical drama Doc – Nelle tue mani, playing Carolina Fanti.

[8] In 2022, Grannò had a main role in the second season of the HBO anthology series The White Lotus as aspiring lounge singer Mia.