Beatrice's siblings included: Frederick III the Simple, Euphemia, Constance (both regents of Sicily), Eleanor, wife of Peter II of Aragon, Louis of Sicily, and Blanche, Countess of Ampurias.

Beatrice's paternal grandparents were Frederick III of Sicily and Eleanor of Anjou, daughter of Charles II of Naples and Maria of Hungary; maternal grandparents were Otto III of Carinthia and his wife Euphemia of Legnica, daughter of Henry V, Duke of Legnica and Elisabeth of Kalisz.

[1] However, the betrothal was cancelled by John Henry's mother who decided to settle with the new Habsburg rulers of Carinthia instead.

[1] In 1345, Beatrice married Rupert, Count Palatine of the Rhine from the House of Wittelsbach.

Beatrice's mother-in-law Irmengard of Oettingen lived as a nun in the convent at Worms.