Bee Branch is an unincorporated community and census-designated place (CDP) in Van Buren County, Arkansas, United States.

When the post office moved in 1879 near the present-day intersection of U.S. 65 and Highway 92, it applied for the name Crossroads, but was rejected as it had already been duplicated in several parts of the state.

The name Bee Branch was chosen for a large beehive in a tree near the post office.

[10] Arkansas State Representative Kim Hammer, a Baptist clergyman from Saline County, was reared in Bee Branch and graduated from South Side High School.

Amber Straughn, NASA astronomer and James Webb Space Telescope Deputy Project Scientist, was raised in Bee Branch and graduated from South Side High School in 1998.