[6] He currently lives in Marin County, California with his wife, Katayoun "Katty" Amjadi (also known as Catherine Vossoughi).

[7] He started acting in films with Samuel Khachikian in Toofan dar Shahre Ma and Abbas Shabaviz's Gole gomshodeh (1962), and became a major star as the brooding hero of the revenge drama Qeysar (1969), directed by Masoud Kimiai.

Vossoughi's most acclaimed performance was as Zar Mohamad, a peasant seeking justice in Tangsir (1973) directed by Amir Naderi.

He was one of the first Iranians to appear in American and European co-productions, such as Caravans (1978), co-starring with Anthony Quinn, Jennifer O'Neill and Michael Sarrazin.

His most famous film works are Qeysar (1969), The Invincible Six (1970), Reza Motori (1970), Dash Akol (1971), Toughi (1971), Deshne (1972), Baluch (1972), Tangsir (1973), The Deer (1974), Zabih (1975), Mamal Amricayi (1975), Kandoo (1975), Hamsafar (1975), Sooteh-Delan (1978), Caravans (1978) and Sphinx (1981).