[15][32][33][34] In 2015, Goldacre moved to the Nuffield Department of Primary Care Health Sciences's Centre for Evidence-Based Medicine at the University of Oxford, joining a project funded by a grant from the Laura and John Arnold Foundation.

[42] In 2020, Goldacre was, with Liam Smeeth, the principal investigator of the OpenSAFELY collaboration which created a software platform to analyse the records of 24 million NHS patients to provide detailed risk factors for hospital deaths from COVID-19.

[47][48][49] Goldacre has criticised anti-immunisation campaigners (particularly followers of Andrew Wakefield such as Melanie Phillips[50] and Jeni Barnett),[51] Brain Gym,[52] bogus positive MRSA swab stories in tabloid newspapers,[53] publication bias,[54] and the makers of the product Penta Water.

[58] In an interview with Richard Saunders of the podcast Skeptic Zone, Goldacre said, "Nutritionists are particularly toxic because they are the alternative therapists who, more than any other, misrepresent themselves as being men and women of science.

It was positively reviewed by the British Medical Journal (BMJ) and The Daily Telegraph, and reached the Top 10 bestseller list for Amazon Books.

"[74] His second book, Bad Pharma: How Drug Companies Mislead Doctors and Harm Patients, was published in the UK in September 2012 and in the United States and Canada in February 2013.

When trials throw up results that companies don't like, they are perfectly entitled to hide them from doctors and patients, so we only ever see a distorted picture of any drug's true effects.

In their forty years of practice after leaving medical school, doctors hear about what works through ad hoc oral traditions, from sales reps, colleagues or journals.

[78] He also wrote the foreword to a reissue of Testing Treatments: Better Research for Better Healthcare by Imogen Evans, Hazel Thornton, Iain Chalmers and Paul Glasziou, published by Pinter & Martin in March 2010.

[82][83] In June 2012, he collaborated with the Behavioural Insights Team of the UK government on a policy paper on the use of randomised controlled trials,[84] and in May 2013, he wrote the foreword to the 'Official Guidebook' of the Romney, Hythe and Dymchurch Railway.

[85] In March 2014, he worked on a systematic review of the side effects of statins compared with placebos, published in the European Journal of Preventive Cardiology.

[89] Goldacre has also appeared on Geoff Marshall's YouTube channel expressing his love for railways during an episode about the least used station in Oxfordshire, Finstock.