In 2012, Hampton was promoted to Melbourne's full-time squad and selected to captain the Queensland under-20 rugby league team in the inaugural U20 State of Origin match.

Hampton made his NRL debut for the Melbourne Storm in round 15 against the Gold Coast, where he scored Melbourne's two tries, made an impressive try saving tackle on Ashley Harrison and took on the kicking duties after senior playmaker Gareth Widdop was stretchered from the field.

[6] He finished off the season with three matches and 1 try for the Melbourne Storm,[7] playing most of the year for the Sunshine Coast Falcons in the Queensland Cup.

[8] On 2 October, in the 2016 NRL Grand Final against the Cronulla-Sutherland Sharks, Hampton played off the interchange bench in the Storm's 14–12 loss.

On 1 October, Hampton started on the interchange in the Cowboys' 2017 NRL Grand Final loss to his former club, the Melbourne Storm.

[citation needed] This season Hampton played three games for the Cowboys' Cairns based feeder club, the Northern Pride, scoring one try.

Due to an injury to Lachlan Coote, he began the season as the club's starting fullback, playing the first five games of the year in the position.

[17] In Round 5, Hampton played on the wing for the first time in his NRL career in North Queensland's loss to the Melbourne Storm.