He is known for his versions of works by Shakespeare,[4] Anton Chekhov,[5] Jean Genet,[6] and Tennessee Williams,[7] as well as his stagings of contemporary writers such as David Harrower, Martin Crimp,[8] Marius von Mayenburg,[9] Caryl Churchill[10] and Sarah Kane.
Key productions include his production of Chekhov's Three Sisters which won the Critics Theatre Award in 2012 for Best Director,[15] Groß und Klein[16] (STC, 2011) for which Andrews received the 2011 Helpmann Best Director award for the third time and which toured to Théâtre de la Ville (Paris), The Barbican (London), the Wiener Festwochen (Vienna) and the Ruhrfestspiele (Recklinghausen).
His production of Tennessee Williams' A Streetcar Named Desire[7] (with Gillian Anderson and Ben Foster[17]) at London's Young Vic opened at St. Ann's Warehouse, New York City, in April 2016.
His STC production of Jean Genet's The Maids (with Cate Blanchett, Elizabeth Debicki and Isabelle Huppert) was played as part of the 2014 Lincoln Center Festival in New York City.
[22] In November 2014, it was announced Andrews would make his directorial debut on Una starring Rooney Mara and Ben Mendelsohn, an adaption of the Broadway play Blackbird by David Harrower.