She was known for having introduced American avant-garde artists of stage, music, dance, and the visual arts to France, and was instrumental in the European careers Merce Cunningham, Robert Wilson, Philip Glass, and Trisha Brown, amongst others.

A 1985 article about her in the Christian Science Monitor, described her less formally as "a combination of friend, agent, impresario, producer, fund-raiser, and creative adviser."

After completing her studies at the Sorbonne in 1950, she worked at a municipal library in Paris and at the bookstore-gallery La Hune [fr], a gathering place for Parisian intellectuals.

She was instrumental in organizing the first European tour of his dance company and its Paris debut at the Théâtre de l'Est parisien [fr] in 1964.

In 1972 she helped him found the Festival d'automne à Paris [fr], an annual multidisciplinary showcase for the contemporary arts.

During Guy's tenure as Minister of Culture, Pesle also convinced him to commission Philip Glass and Robert Wilson's opera Einstein on the Beach which had its world premiere at the Festival d'Avignon in 1976 and toured to Hamburg, Paris, Belgrade, Venice, Brussels and Rotterdam later that summer.

[4]Her funeral was held on 24 January 2018 at the Église Notre-Dame-des-Champs in Paris and her ashes interred in the family tomb at the Montparnasse Cemetery.

[12][13] The main archive of her papers is held at the Institut mémoires de l'édition contemporaine in Caen and includes a detailed documentation of her work with Merce Cunningham from the beginning of their collaboration in the early 1960s until his death in 2009.