Pedretti began his career at FC Sochaux-Montbéliard in 1999, in the club's youth system, and in the same year, he played his first professional match.

The team also had a strong cup run that year, reaching the final of the Coupe de la Ligue, but losing 4–1 to Monaco.

Pedretti only amassed 21 appearances in all competitions and was often denied a place by the likes of Florent Malouda and Juninho Pernambucano spending much time on the bench.

He continued to show good performances, especially during the quarterfinals of the League Cup where he scored a decisive goal in stoppage time against his former team Marseille.

After the end of the season, Pedretti stated his desire to leave Auxerre with league title holders Lille OSC being his preferred club.

Pedretti was signed by Lille OSC for an undisclosed fee on the opening day of the summer 2011 transfer window as a replacement for Newcastle United-bound Yohan Cabaye.

[9] On 20 November 2002, Pedretti made his debut for the France national team that year, coming on as a late substitution for Lilian Thuram in a 3–0 win over Serbia and Montenegro.

[10] He was part of the French squad that won the Confederations Cup in 2003 and reached the quarter-finals at Euro 2004 when France were knocked out by the eventual champions Greece in the quarter finals by the score 1–0.